Immunology Methylation Panel
Analysis of the percentage methylation levels of multiple genomic loci showing the relationship between immunology and DNA methylation
The Immunology Methylation Panel measures methylation levels of CpG sites at multiple regions in the genome important for the function of the immune system. We achieve this by bisulfite modification and multiplex PCR followed by Next Generation Sequencing.
The assays in this panel are pre-validated to ensure no preferential amplification for either methylated or unmethylated DNA, providing the quantitation of DNA methylation at base pair resolution.

Step 1: Select Your Targets
Choose from our carefully designed panel of 16 genes, and choose some of your own targets. We will design and validate any additional assays you choose to add to the panel.
For Treg-related genes,
see our FOXP3 Methylation Panel
Information: Immunology Methylation Panel | |
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Species: | Human (Homo sapiens) |
Stats: | 95 CpG sites over 16 genes using 20 amplicons |
Full Gene List: | TNFRSF25, IL2, IL4, IL7R, CD247, CD40, IL1B, TNFRS10C, IL8, CD44, CXCR3, TNF, IL13, MMP1, MMP3, MMP13 |
Panel Summary: | Download our full list of NGS methylation assays offered in the Immunology Methylation Panel. |
Step 2: Choose an Ideal Plan for You
Choose the services that are appropriate and ideal for your needs. All parts of our methylation services are customizable and modular. We offer services in:
Items | Service Products | Description | Order |
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8200 | Custom NGS Assay Design | Assay design based on customer-submitted target region(s).
|
Inquiry / Order |
8500 | Targeted Next-Gen Sequencing – Standard | Custom target gene sequencing using Ion Torrent instruments:
|
Inquiry / Order |
8501 | Targeted Next-Gen Sequencing – Premium | Custom target gene sequencing using Ion Torrent instruments:
|
Inquiry / Order |
8100a | NGS Data Analysis | Preliminary data analysis of NGS generated sequencing data. | Inquiry / Order |
Step 3: Results
EpigenDx analyzes the raw data and delivers:
- The percentage methylation values of each CpG site in a Microsoft Excel spreadsheet.
- Sequencing data in a FASTQ file.
Interpretation of Data
Methylation data can then be applied to research. For example, increased DNA methylation at specific CpG sites in the promoter region of genes is a hallmark of many cancers.
Speak with experts at EpigenDx for high quality technical support and consultation through all phases of the project, from assay design to data delivery.