BDNF Methylation Assays
The BDNF gene encodes a protein called brain-derived neurotrophic factor. It is a neurotrophin, or nerve growth factor, that promotes the survival of existing neurons and the formation of new neurons from neural stem cells. The BDNF gene has eight different promoters and eight possible transcripts.
EpigenDx offers BDNF gene methylation assays and analysis services, which cover a total of ten gene regions within BDNF and 101 CpG sites.
Human BDNF: This gene structure zooms in on three particular areas of the BDNF gene. Red markers are CpG sites covered by at least one of EpigenDx’s pre-developed assays (ADS). Blue X’s are all other CpG sites.
Applications and Advantages
Bisulfite Based DNA Methylation Analysis
- Bisulfite sequencing using Next Generation Sequencing or Pyrosequencing
- HRM analysis with custom optimization
- COBRA Methylation Analysis with custom optimization